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首页» 化学生物与药物化学实验室» 科研成果
 

主要论文选:

1. Qin CG, et al. Alternative Mode of Binding to Phosphotyrosyl Peptides by Src Homology-2 Domains. Biochemistry 2005, 44(36): 12196-12202.

2. Qin CG, et al. Optimization of Antibacterial Cyclic Decapeptides. J Comb Chem 2004, 6 (3): 398-406.

3. Qin CG, et al. Facile solid-phase synthesis of cyclic decapeptide antibiotic Streptocidins A-D. Tetrahedron Letters. 2004, 45 (1): 217-220.

4. Qin CG, et al. Dissociation of antibacterial and hemolytic activities of an amphipathic peptide antibiotc. J Med Chem 2003, 46 (23): 4830-4833.

5. Qin CG, et al. A chemical approach to generate molecular diversity based on the scaffold of cyclic decapeptide antibiotic Tyrocidine A.  J Comb Chem 2003, 5(4): 353-355.

6. Qin CG, et al. Isolation and characterization of a novel polysaccharide from the mucus of the loach, Misgurnus anguillicaudatus. Carbohyd Polym 2002, 49 (3): 367-371.

7. Qin CG, et al. Protective effect of polysaccharide from the loach on the in vitro and in vivo peroxidative damage of hepatocyte. J Nutr Biochem 2002, 13 (10): 592-597.

8. Qin CG, et al. Synthesis of Gramicidin S and its analogues via an on-resin macrolactamization assisted by a predisposed conformation of the linear precursors. J Org Chem 2004, 69 (8):2681-2685.

9. Qin CG, et al. Effect of Misgurnus anguillicaudatus polysaccharide on immune responses of splenocytes in mice.  Acta Pharmaco Sin 2002, 23 (6): 534-538.

10. Qin CG, et al. Component analysis and molecular weight determination of  Misgurnus anguillicaudatus polysaccharides by gel filtration chromatography. Chinese J Anal Chem 2002, 30 (4): 411-413.

11. Qin CG, et al. A novel oligosaccharide from the mucus of the loach. Chinese Chem Lett 2002, 13 (4): 321-324.

12. Qin CG, et al. Effects of the leach polysaccharide on removal of reactive oxygen species and  protection of DNA chains. Acta Bioch Bioph Sin 2001, 33 (2): 215-218.

13. Niu WN, et al. Secretion of Pro- and Mature Rhizopus arrhizus lipases by P. pastoris  and properties of the proteins. Molecular Biotechnology,2006,32(1):73~82.

14. Niu WN, et al. Improved thermostability and the optimum temperature of Rhizopus arrhizus lipase by directed evolution  Journal of Molecular Catalysis B: Enzymatic,2006,43:33-39.

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